Synergistic Red Fuse ...

Huh? Are there really ANY cases where aftermarket fuses failed to protect the equipment? I haven’t heard of any, maybe you have an inside track. As for stock fuses degrading the sound they will, like aftermarket fuses, degrade the sound less when they are inserted in the correct direction. There are in fact a number of things one can do with stock fuses to improve their performance including addressing RFI/EMI, vibration and magnetic fields as well as employing a better fuse holder and employing contact enhancer on the fuse caps.

I can understand the reluctant position that some people have towards fuse upgrading   There hasn't been a clear and acceptable technical explanation provided. This will conflict with the logic and use of reason for technically oriented people, I get that.  In audio I've come to recognize that there are outcomes and results confirmed via direct listening that lack satisfying  explanation.  

This disconnect doesn't bother me as it would some other listeners. I just accept that you can not always explain the why or the how of certain phenomenon.  I don't even attempt to explain why the Red fuses  have the effects that they clearly do.  I just don't know to be blunt, all I can do is tell others what I hear,that's as far as I can go. Something is happening on a technical level for these fuses to contribute in the way they do. 
I trust what I hear and acknowledge I can't tell someone why they work so well. I'm simply very happy these products exist and I'm able to buy and enjoy them. To be able to tweak and improve your current system without spending  multiples more money in changing components is a legitimate cause for celebration and appreciation. 
Charles, 

@charles1dad;
I totally agree with your comment above.
Similar to the way interconnects, speaker cables, power cords and AC outlets etc, can make ones system sound different in a positive way or negative way. I also can’t explain why, but I know what I hear.

I don’t know how it works but works it does! What almost every reviewer says about whatever tweak or device he’s reviewing. I find it a little bit hard to believe that none of the aftermarket fuse manufacturers provide any explanation for how their product works. We already know for example that wire directionality is part of it. Anyone wish to take a stab at other things aftermarket fuses do better than stock fuses? Thimk, thimk!

Oregonpapa, how many hours would you guess you put on the fuses before you felt they were broken in?