I heard them recently at a CES show in Hong Kong. They were matched with Jeff Rowland pre and power amps, and cardas cables.
I have the Eidolon Vision speakers at home, and I thought the Avalon Time was quite a bit (not marginal) better than my Eidolon Visions. If ultra expensive, high-end speakers are all about the ultimate finess and refinement in sound quality, then I think Time has achieved that. Time was even more refined and delicate in sound, had much better high-end extension, and most noticeable was the much improved bottom end and dynamics versus the Visions, making Time overall a much better full-range speaker. Huge soundstage and very holographic sound was still there with Time -- the very hallmarks of Avalon speakers which I enjoy.
Although I have never heard the Isis, I have heard the Indra, which I thought was a big notch below Vision. But at about 2x the price of Eidolon Vision, I would still buy the Time speakers if money was no object....but then again, isn't that always the irony in life?.....:-)