Some of the most expensive cables made, such as Jorma and MIT use copper exclusively. IMO, some cable makers may use silver-plated wires only to be able to use the word "silver" in their marketing. I don't think we, as consumers, have the opportunity to compare the exact same cables with copper v. silver-plated wire, so it's probably impossible to tell for sure. But I'm open to the concept that silver-plated wire may sound different than pure copper.