I own a pair of Thiel 22's and I would strongly agree with most that your front end and then cables are probably your problem. I'm using the CAL Delta/Alpha comb with MIT speaker cables.
Theil/Classe 6, and listener fatigue
I have Theil 2.2 speakers, a Rotel 855 CD player, a B&K 442 amp, and recently replaced a B&K pro 5 with a classe 6 (a later model than the DR). There is much more detail to be sure but it comes at the expense of fatigue. The highs are either too bright or edgy. Any advice would be greatly appreciated.