FYI and interest:
With your 2250 and your LK280 there should be no issue bi-wiring your speakers.
Both of these units have similar plugs for output. Generally speaking,for the sake of uniformity, I would not be quick to mix balanced and unbalanced connections in the same system.
In this case, both units have unbalanced outputs, the LK28 would use banana to banana and the 2250 would use compliance plugs to banana.
This would be uniform and there should be no issues with this match.
With your 2250 and your LK280 there should be no issue bi-wiring your speakers.
Both of these units have similar plugs for output. Generally speaking,for the sake of uniformity, I would not be quick to mix balanced and unbalanced connections in the same system.
In this case, both units have unbalanced outputs, the LK28 would use banana to banana and the 2250 would use compliance plugs to banana.
This would be uniform and there should be no issues with this match.