IMHO, the most pernicious effect of the room acoustics is the extended decay at certain frequencies. These frequencies are not necessarily those that show up as instantaneous magnitude peaks nor, if they do, is simply reducing the magnitude going to reduce the decay time appropriately. Ideally, one would like to have a room with a uniform decay time (analogous to RT60) for all frequencies but this is more difficult with small rooms (at home) than it is with large ones (concert halls).
Kal