It must also be said that many designers are not going to give away
their particular paradigm or trade secret while others do have white
papers and measurements galore it is a complex issue. Ultimately it is
your own listening judgement and I urge you to try experimenting. The
relatively inexpensive DH Labs bulk DIY cable is a great place to start.
No, it's not a complex issue. A power cord is a very simple issue. Building an actual power amplifier IS a complex issue. Power cords, speaker cables, etc. are not complex at all.
What is really complex is our brains and the physiology of our acoustic system and perception. Every time I have a couple of beers my system sounds so much better.