Age or the amount of owners are irrelevant condition is whats important as were pointed out.
Depending how old speakers are original foam surrounds can be a concern. As can replacement surrounds depending on replacements, were they done with quality accurate duplicates made by a company for a specific driver or one size fits all flea market type surrounds. And were the replacements installed by somone reputable or atleast someone that cared enough to do a good propet job. This should reflect in asking price or make or break the sale.
Also wire coatings can dry out and become brittle and crack over time and cause a short in extreme cases.
Capacitor age might also be a concern, they dry out in time as well, some sooner than others. Poly caps tend to last longer.
None of these should become a concern unless reaching over a decade plus. Or depending on where the speaker lived its life thus far. Sunlight and tempatures can play some part in it.