I seriously doubt this is a source issue. If I were you I'd attack the problem directly. Find a way to borrow another integrated and pair of cone speakers and swap them one at a time. If either solves your problem you have your answer. My first thought was that that this sounds like it's being caused by some unintended digital room correction or, as others have mentioned, a phase inversion issue. Changing equipment and re examining wire connections (which you've already done) will obviously rule out these possibilities.
Then again this could be a perception issue since you don't listen to vocal recordings as much. Do ALL vocals sound like they're "in back?" By "in back" do you mean they sound physically behind the instruments or that they sound lower from a volume perspective, or both? Some speakers are designed to put you in row three of a performance where things seem to be more right in front of you, and others put you further back so you "see" the performance as a whole in the context of the venue and the sound typically comes more from behind the plane of the speakers (I suspect your Tylers are more the latter). When you move the Tylers closer to the back wall do the vocals sound any better to you? If you put on something like a Diana Krall studio recording and she's not front and center you definitely have some other issue. Anyway, hope this helps in some way and best of luck!
Then again this could be a perception issue since you don't listen to vocal recordings as much. Do ALL vocals sound like they're "in back?" By "in back" do you mean they sound physically behind the instruments or that they sound lower from a volume perspective, or both? Some speakers are designed to put you in row three of a performance where things seem to be more right in front of you, and others put you further back so you "see" the performance as a whole in the context of the venue and the sound typically comes more from behind the plane of the speakers (I suspect your Tylers are more the latter). When you move the Tylers closer to the back wall do the vocals sound any better to you? If you put on something like a Diana Krall studio recording and she's not front and center you definitely have some other issue. Anyway, hope this helps in some way and best of luck!