Best Speaker cable in the $400.00-$500.00 range for 2 meters

Well, since OP so far not willing to specify what kind of improvements he's looking for, I'll submit there's a 2m pair of Acoustic Zen Hologram II on eBay for $599.  Great all-around cable I'd think would be tough to beat at that price.  But then since we don't know the OP's tastes, who knows???  Just a crap shoot here. 

Hi.  72 year old seasoned music lover.  I spent much time with a local cable designer in Maine who went up against the big boy stuff.  My most recent find has been working with Tim Stinson of Luminous Audio, a small, dedicated specialty company that has fair pricing and wonderfully musical, revealing products.  Highly recommended, kjl1065!
 

Kimber 8TC

I have to agree with those suggesting that your choice of cables should be dependent upon your current system and where you want the sound to go from where it is now.  

For example, Analysis Plus cables were recommended by one poster.  I find their cables to be a bit on the warmer side and recall purchasing a pair several years ago when my system was a bit bass shy.  They were perfect at that time and did exactly what I had hoped.  

On the other hand, I've found cables like Kimber and Nordost to be on the cooler side.  If you feel that your system is a bit too warm, or that you need more enhanced resolution, that type of cable might work well for you.

The cables that I've personally used and have found fairly neutral have been ones like Transparent Audio and Clear Day.  Another poster is correct that Paul of Clear Day isn't currently assembling cables.  Sending a shout out to him, and hoping that his health improves very soon!  Michael

@wcfeil "Expect 50 responses with 50 different recommendations."

Best and most accurate post of the year in any thread, and will not be eclipsed