They are physically interchangable, being 9 pin minuture dual triodes. They are not electrically interchangable however, so you should probably refrain from substituting one for the other.
If you search the forum you will find the question being asked over and over again, and hundreds of great suggestions as to which is the best 12AX7 and 12AU7 type tubes.
IMHO, it is also very context dependent so you should search for suggestions for the tube types that work best in the specific gear you are using. Without knowing this the question is a bit like asking what the best tires are without knowing if you drive a sports car, light truck or tractor.
If you search the forum you will find the question being asked over and over again, and hundreds of great suggestions as to which is the best 12AX7 and 12AU7 type tubes.
IMHO, it is also very context dependent so you should search for suggestions for the tube types that work best in the specific gear you are using. Without knowing this the question is a bit like asking what the best tires are without knowing if you drive a sports car, light truck or tractor.