My system's high frequencies hurt my ears

Well, to be perfectly clear it doesn't always hurt my ears but I've been getting a little fatigued at times and I'm trying to diagnose the problem. A few nights ago I was listening to a new 24/96 The Doors first album release and had to stop playback. I switched over to The Eagles Greatest Hits, 16/44, and found some happiness there but I wasn't completely satisfied. Perhaps some of this is psychological, maybe I was feeling a little extra sensitive, but I'm sure I've had some issues with high frequencies in the past.

Here's my setup:

Serving all music, ripped to WAV by Exact Audio Copy or downloaded via high rez sites, via Windows 7 computer running J River set to WASAPI output. Sending signal via USB to Audiophilleo USB/SPDIF converter to PS Audio Digital Link III DAC. From DAC using Nordost Baldur unbalanced RCA interconnects to PS Audio C-100 Control Amp. Speaker wires are Nordost Blue Heaven. Power cables are PS Audio Lab Cable from wall to PS Audio Duet Power Conditioner. From there I use another Lab Cable for the amp and a PS Jewel cable for the DAC. The wall plug is on its own circuit with nothing else connected. Speakers are my old but good Mirage 1090i's.

Aside from perhaps the age of the speakers do you guys see anything that stands out? I spoke to a technician from Mirage and he suggested I'm doing too much signal processing which could be a cause of uncomfortable high frequencies.

Looking forward to hearing your thoughts.