ryllau, there are many pre's that have more than one set of main output connectors. but, i woodn't necesarily use this as the criteria for choosing a preamp. there are quality adaptors that allow ewe to connect a pair of i/c's to one output. even tho my pre has *three* outputs, i still have to use adaptors, because i use an active x-over which has only one set of hi-pass outputs. i run a pair of amps from my hi-pass outs to wertically bi-amp my monitors.
but, when bi-amping, ewe *do* have to be even more aware of impedance mismatches - adding a second amp to yer pre effectively lowers the input impedence the pre is seeing. for example, if ewe are using two amps rated at 20k-ohms input impedence, the preamp will *see* a 10 k-ohm impedence. and, longer i/c's, which can be attractive in a wertically bi-amped set-up, to reduce the length of the speaker cable, can further exacerbate any impedance mismatches. basic rule of thumb is that yer amps' input impedance needs to be *at least* ten times greater than the output impedance of the preamp, & in some instances, even this amount may not be enuff.
hope this helps, doug s.