The simplest, and safest way is to use one power amp, and use your second source as an input to your main preamp. I'm not sure is this gets you what you're after though since you didn't provide details. You may want to describe your situation in detail.
Whatever you do, do NOT have 2 power amps connected to the same speakers at the same time, unless the amps are isolated from each other by a switch.
Whatever you do, do NOT have 2 power amps connected to the same speakers at the same time, unless the amps are isolated from each other by a switch.