I once owned Silverline Sonata III loudspeakers, which Alan Yun the owner of Silverline, adamantly stated were designed to be bi-wired and sounded best bi-wired. I bi-wired them for a year or so, until I decided to try some new cabling. For the new cabling, I ordered a bi-wire pair, and a single wire pair with matching jumpers.
I preferred the single wire connection. To me, the sound had better focus, and the speakers disappeared better, so I kept the single wire pair and returned the bi-wire pair.
The point being that even on speakers designed for bi-wiring, it pays to try both methods with the same cabling and decide for yourself which method sounds best.