Capacitance, impedance and resistance all affect a cable's sound. Thickness and length of the cable, as well as the construction and materials in the cable will alter capacitance, impedance and resistance.
So, the answer to your question is that thicker cabling will likely sound different, but without specific specs on what you presently have and what you'd like to try, a comparison is impossible.
Higher capacitance generally results in a roll-off of highs, and a more closed-in sound.
The manufacturer of my speakers (Silverline Audio) sells his own speaker cables which he has matched to the speakers. The cables are pretty small, and are comprised of small conductors. He insists that a length of 10-15 feet is optimal, and that anything shorter than 10 feet is not good. I don't know if his philosophy applies to all speaker cables or to just his.
So, the answer to your question is that thicker cabling will likely sound different, but without specific specs on what you presently have and what you'd like to try, a comparison is impossible.
Higher capacitance generally results in a roll-off of highs, and a more closed-in sound.
The manufacturer of my speakers (Silverline Audio) sells his own speaker cables which he has matched to the speakers. The cables are pretty small, and are comprised of small conductors. He insists that a length of 10-15 feet is optimal, and that anything shorter than 10 feet is not good. I don't know if his philosophy applies to all speaker cables or to just his.

