Sebollo, M22 and Bel Canto Ref600 are completely different designs... Different manufacturer, different circuits, and likely different modules. I would not venture to guess sound of REF600 based on listening to M22.
In general, NCore tends to have a high input impedance, hence compatibility with upstream devices should not be an issue. REF600 in particular, seems to have an input impedance of 200KOhms.... So upstream compatibility should be a non issue.
Downstream, NCore appears to have a damping factor between 500 and 1000, so it is possible that it works best for speaker with normal or lower input impedance... For my Vienna Die Muzik, NCore is a wonderful match.
Regards, G.