With tube rectifier things get simpler because tube rectifiers reach operational voltage slow enough to catch problem with or even without variac.
With variac set to operational voltage and voltmeters attached to the bias pots or resistors and one attached to the rectifier output you can monitor gradual voltage increase. Once bias on any of the bias pots goes beyond tolerant, you can bring back variac to the noted voltage or below or turn amp off and inspect circuit elements around the fault bias pot or resistor.
With variac set to operational voltage and voltmeters attached to the bias pots or resistors and one attached to the rectifier output you can monitor gradual voltage increase. Once bias on any of the bias pots goes beyond tolerant, you can bring back variac to the noted voltage or below or turn amp off and inspect circuit elements around the fault bias pot or resistor.