Top 5 Hamburgers

Macdad

Love that place. I also love Joe Boston's in Chicago for Italian Beef and the Gibson Brothers in Santa Maria style tri-tip.

Concerning Houston, I love Dot's Coffeeshop for their chicken fried. Amazingly good.

I don't know Macdad, the best sandwich? I'd have to say it came from a Jewish deli, like
5) Art's in B.H. or Studio City
4) Mort's in Pacific Palisades
3) Shep's on Pico (I think it's gone)
2) Carnegie (N.Y.)
1) Webbie's on Laurel Cyn and Ventura (*sniff* gone...)
and was probably a hot brisket/pastrami combo with coleslaw, swiss cheese and Russian dressing on rye or onion.
Or maybe a tongue/liverwurst combo.
Non Jewish deli mentionables:
The Tam O'Shanter on Los Feliz has a GREAT sandwich board, and is a pretty good restaurant too. Owned by Lawry's, so the prime rib is terrific, too.
Here in Phoenix there are a couple of places, Luke's and Guido's, that make outstanding Italian beef/sausage combo sandwiches (ALWAYS with peppers and provalone).
My dad was born and raised in Upper Darby, Pa. I have no excuse for not getting over there one day to try real Philly cheese-steak.

Azuad, since you mentioned deli sandwiches in L.A., I would recommend Brent's Deli in Northridge above Art's Deli (considerably so, IMO), and also an L.A. institution for pastrami, Langer's Deli near McArthur Park.

In a pinch, my wife and I go to Art's. We live about four miles from there...but given the time, we drive the 15 miles to Brent's. Give it a try!

Agree with Brent's. Super great hand cut lox.

Best Sandwiches:
Italian: NYC: Bar Stuzzichini, Defontes, Porchetta, Terroir, Torrisi
Chicago: Birchwood Kitchen, Joe Bostons
SF: Cane Rosso, Ironside, Orson, Sandbox Bakery, The Refuge
LA: Phillipes, Santa Fe Importers, Langers, Bay City, Claros, D' Elia's (Best bread ever)
LV: Snacks
Philly: Chinks, Dalessandros, Jim's Steaks, John's Roast Pork
New Orleans: Domilise's, Mothers