HOW TO POSITION 2 PAIRS OF SPEAKER FOR ALTERNATE LISTENING

Oh, wolfie, you are a bad man...

@infinity_audio 
I think you are just going to have to accept that there will be some interaction with the adjacent speaker. But, then everything in the room will contribute to affecting sound reproduction.
If it were me, I would try to set up each pair as best as possible and not concern myself with any interactions. You can only do so much...
Bob

I did tried it, it isnt too bad. I align them on the same line, but both has different toe-in. The outside pair sounded much better, the inside pair got slightly congested.

Did you try reversing positions?
Do all the permutations, if possible.
B

Infinity I usually have speakers to rotate, what I do, I move forward the one Iam using at least 5 inches... I get good result when I do that....

According to Jim smith, you never want more than 1 pair of speakers in a room. The driven pair will start to move the cones of the standby pair