specifically the ones that replace the spikes as opposed to the stands?
Always spike into a cement slab floor, especially if it’s laid on mother earth.
Good test if you can feel through your bare feet drop something heavy dropped on the floor, if not spike into it, if you can feel it don’t spike (couple), as the floor will become a sound board for the bass notes and muddy the bass.
Best in this situation is to isolate (decouple) the speaker from the floor, numerous ways, cheapest I found without being ripped off by "audiophile products" is with heavy duty "Sorbothane" pads like these, there many if you search, 4 of these "70 duro" will take a 52kg speaker.
https://www.ebay.com/itm/NEW-SRM-TECH-SORBOTHANE-ISOLATION-RINGS-HEAVY-DUTY-70-DURO-4-PACK/332856500...
https://www.ebay.com/sch/i.html?_from=R40&_trksid=p2334524.m570.l1313.TR2.TRC0.A0.H0.Xsorbothane...
Whatever you do DON"T put your speakers on springs, they'll wobble around like jelly, and your image will be shot to hell.
Cheers George