When you have separates, the equipment does not have to share power supplies. This reduces intermodulations and for that reason alone allows for better sound.
But there are additional benefits- frequently separates have better power supplies, better heatsinks (in the case of transistor amps), usually better quality parts and overall better circuits.
But there are additional benefits- frequently separates have better power supplies, better heatsinks (in the case of transistor amps), usually better quality parts and overall better circuits.

