@djones
I have never owned a tube amp , always used SS and this doesn't come up if it's rated for 8 and 4 Ohm. I have what is I am sure a novice question. My speakers are 6 Ohm and I notice most tube amps have 4 Ohm or 8 Ohm taps and sometimes 2 Ohm. Where would I connect a 6 Ohm speaker?
Here is where experimentation will produce very real and obvious results. Always use the lowest tap that gives you enough volume without distortion (clipping). You will then get the most damping and the speaker will have frequency response as close as possible to the designers voicing. If you want more detail on why that is ask me. Its long.
Also experiment with the taps at low listening levels where clipping will not be an issue. Listen for tonal changes and peaky or mushy bass. The bass is most affected.
FInd an impedance curve for your speaker and send me a link. Impedance variations are the largest cause of response variations with most tube amps and tap choices.

