Hi,
The differences between the two designs can be seen clearly on our web, as we have posted pictures of the internals. The Anaconda uses a dual-HELIX weave, meaning two hollow core braids are interlaced with sixteen counter-rotating conductors. The sum total is a 7 gauge aggregate design that is light-weight and easy to maneuver.
The Python is a slightly smaller, 9 gauge aggregate single core braid that is far easier to braid by hand. I am very comfortable with that cord being compared to _anything_ on the market, commercial, internet or DIY.
The Purist Dominus is a fantastic power cord-- from my experience a few years back, as are the Elrod cords--both worthy products deserving of an audition. IMO, Jim Aud and David are designers that deserve support. I'm not familiar at all with the latest e-glide products.
Follow sound procedure, no quick ins and outs, allow settling time and let the music decide.
Best wishes.