Do long interconnects degrade sound?


I recently moved into a new home and I would like to use my Krell 400xi intergrated as a preamp for my main speakers in my living room (PMC OB-1). The Krell has a preamp out. Currently the Krell is powering my main speakers for my plasma in my den. In addition, my source is also in my den. Ideally, I would like to use the Krell for both applications which would mean that I would have to run extremelly long interconnects from my amp in the living room to the Krell in the den. I know XLR's would be best for long runs, but is 50+ feet too long for interconnects?
jla
This seems to be a controversial topic.

In the good old days, longer interconnects and shorter speaker wires were considered a tweaky must for any self respecting audiophile.

Later, some people tried to convince me that it was a bad idea.

Most recently, I deferred to Signalcable.com who suggested that runs of up to 50' should be no problem, at least for my ARC SP-11 Mk II preamp running into my Levinson 23.5 amp.

I think I, therefore, increased the length of my interconnects to as much as 40', which is working just fine.

Other people may have more technical advice here, but I have never had a problem with this configuration.
I agree with Cwlondon, your Krell should drive 50 feet of low capacitance interconnect with no problem. If you want to be sure, check the specification of the chosen interconnect (at final length) and call Krell with the data.

Most high end cables are so low capacitance that even 50 feet would effect highs (roll off) only above approximately 100 Kh. It's even less of an issue with balanced because the output impedance is generally very low (600 Ohm), making the load even easier.
Thanks guy's for the great advice! My wife wants all the electronics in our den, but I don't want to run 50+ feet of speaker cable to my OB-1's in our living room since I am sure this would degrade the signal. I am looking to purchase some small mono's and I will run long interconnects back to the Krell. Thanks again for your help.