Alexs is correct. Speaker cables typically carry at least 1000X as much current as a interconnect. Re purposing interconnects to speaker cables would be inadvisable in almost all cases.
Don't know why you'd want to. You'd be chewing up a perfectly good pair of interconnects in order to convert them to speaker cables. And besides, its really not quite the same. If you want to try it, then by all means do it. But there's a reason ICs are ICs and speaker cables are speakers cables.
I agree with Alexs. Most (not all) interconnects are typically less than 20 gauge. Interconnects run a very low voltage and current where speakers require a LOT more current. That is why you would want a heavier gauge for the speakers.
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