50' speaker or 50' interconnect?

If you used cheap 50 foot XLR and did not try a LONG break in you are not getting the results possible.
The minimum quality would be the Mogami (not a copy!!) suggested above. The minimum 'audiophile' 50 ft would run you about $1,000. or so (so I WOULD try the Mogami and use it for at LEAST a month or two)
I use a Kimber Hero 7 meter ($700 plus) XLR (half your distance!)
To get a speaker cable that can go 50 ft is going to cost a LOT more for the same quality.. so stick with the XLR IMO.

Ocos speaker cables are supposed to be good for up to 100 meters.
http://www.dynaudio.com/eng/systems/lines/accessories/ocos.php

I'm using about 35 ft of balanced Anti-Cable interconnects from the preamp to the amp with about 4 feet of speaker cable. Sounds great....no noise, big, wide, deep soundstage, etc.

If you are running balanced interconnects, you need to make sure your equipment is also truly balanced to reap the benefits of balanced. An XLR jack does not mean truly balanced, necessarily

What preamp are you using, and if you can readily determine it, what is its output impedance?

The higher the output impedance, the more critical cable capacitance will become. The symptom of cable capacitance that is too high in relation to output impedance would be upper treble rolloff, and its associated subjective effects (sluggish transients, dull sound, reduced ambience, etc.).

I can do some quick calculations for the Mogami once I know the output impedance of the preamp.

Here is a link at which you can purchase a 2534-based 50 foot length of terminated Mogami Gold Studio xlr cable, for $98.95, from B&H Photo Video (an excellent seller). They have a 15 day return policy:

http://www.bhphotovideo.com/c/product/318716-REG/Mogami_GOLD_STUDIO_50_Gold_Studio_XLR_Male.html#features

Blue Jeans xlr cable, based on Belden 1800F, has a bit under half the capacitance of the Mogami, but does not provide the Mogami's quad conductor configuration which improves noise rejection. Some of the higher end cables, such as some Cardas cables, also have considerably less capacitance than the Mogami's, but of course will be very expensive in that length. So I second the suggestion of Mogami unless the output impedance of your preamp is particularly high at high frequencies.

Regards,
-- Al