I should have provided more explanation regarding the Vandersteens. One of the most enjoyable listening experiences ever was a modest pair of 2ce's with subs and Melos electronics at a NY S'phile show. I love their sound, and the music selections and low traffic in that unglorified room didn't exactly hurt, either.
But the time aligned speakers of the usual sort, which to me means first order crossovers and aligned acoustic centers (although I am now told there are other form factors and crossovers to achieve more or less the same thing), by their very nature, in theory, will not be optimal for off axis listening. Audiogon had an excellent thread on this topic. If you read down near the end, Jeff Joseph and the designer (?) from Green Mountain join in to explain their design choices.
http://forum.audiogon.com/cgi-bin/fr.pl?cspkr&1032037028.