Biggest Sound in the Littliest Box

System Audio's SA2k is a pretty impressive performer. It uses customized scan-speak drivers somewhat similar to those used by Wilsons, for example (same driver "family"). Well worth a try in their size/price/performance range.
details at:
http://www.system-audio.com/showpage.asp?siteid=2&id=312

totem mite indeed.

ATC actives.

The brittish excel at building small speakers. Few people over there have the space for large speakers, and monitors are a big industry. The Harbeths and Tannoys are examples.

There are a number already listed that I agree with. I tend to find the "bigger" size is an illusion created by credible bass. As such coupling small speakers with a great subwoofer will increase that illusion further. My office system uses Red Rose R-3 speakers that are isobarik loaded and thus produce far better bass (both deeper and well controlled) than a speaker this size should.