"Ok lets say things do change after "burn in", how does any designer compensate for this, in his calibrations, measurements, tests and design????"
They compensate for this by breaking the prototypes in before they listen and measure. For example, a designer may want to try several different capacitors when building an amp to see which one sounds the best. If they want to try 5 different options, they break the amp in 5 different times. They don't do any serious listening or measurements until they break the amp in first. This is the way they all do it. I don't think you could find one company that doesn't break their equipment like this. You don't have to take my word for it, either. Call some manufactures and ask them.
They compensate for this by breaking the prototypes in before they listen and measure. For example, a designer may want to try several different capacitors when building an amp to see which one sounds the best. If they want to try 5 different options, they break the amp in 5 different times. They don't do any serious listening or measurements until they break the amp in first. This is the way they all do it. I don't think you could find one company that doesn't break their equipment like this. You don't have to take my word for it, either. Call some manufactures and ask them.

