"- so color means boxy, as opposed to open and airy?"
Correct.
"- why is this, what causes it?"
I am not a designer, perhaps others will weigh in. It may be due to the larger baffle and the reflections within the horn throat though.
"- on a different note, do you have any preference between a 300B, 2A3, 45, or EL34, or other amp design with Klipsch's?"
Yes, I do, but I will not go into that. One of the best things about high eff speakers is that they free you to try any of these types of amps and still get good SPLs in a real world room. Paul Klipsch always said what the world needed was a good two watt amp. He liked the Brook push-pull 2A3 amps. I have heard them and they sounded just great, but they are beyond my financial resources. Way beyond. One nice thing is that, if you like the sound, you won't really need a very expensive amp. Even a Dyna 70 will get you there.
"What would you guess would be the real world hearable differences between the two on the low end?"
Room interaction is so unpredictable that I could not begin to guess.
Brownsfan and the other posters bring up a good point, you need to listen to these speakers, as they are certainly not for everyone. Do use a tube amp though. My experience has been that they don't sound very good with SS. Though I have not tried every type of SS amp with them.