There’s a very good (and long) thread on the topic if you search this forum...it will be hours of reading, but thoroughly informative. Search something like “Zu Druid Round-up” maybe? Forget the exact title...
From memory many liked your Sophia with them...I would certainly try that first. My current Soul Supremes have the same drivers and roughly the same specs as the Druid 5s. I’m very successfully using Audion Golden Dream monos (parallel 300Bs), Thoress 845s monos (845s, obviously), and a Melody 845 integrated. All sound fantastic but different due to the tube topology, as you would expect. I bought all 3 based on that thread, I think. I ran a First Watt SIT-2 for about 6 months...the only SS amp I really liked with them, but ultimately never loved it, and sold it a month ago after sitting on it for a couple of years. If solid state is your preference, there’s a new First Watt out that I might try over the SIT if you can demo it...from my reading on it.
From memory many liked your Sophia with them...I would certainly try that first. My current Soul Supremes have the same drivers and roughly the same specs as the Druid 5s. I’m very successfully using Audion Golden Dream monos (parallel 300Bs), Thoress 845s monos (845s, obviously), and a Melody 845 integrated. All sound fantastic but different due to the tube topology, as you would expect. I bought all 3 based on that thread, I think. I ran a First Watt SIT-2 for about 6 months...the only SS amp I really liked with them, but ultimately never loved it, and sold it a month ago after sitting on it for a couple of years. If solid state is your preference, there’s a new First Watt out that I might try over the SIT if you can demo it...from my reading on it.