The 2.2 can certainly benefit from a better cartridge. I'm not familiar with the Ortofon cartridges, so can't say how much of an improvement the specific upgrade you're thinking about will make. I have a Nagaoka mp500 on my 2.2 and it sounds really nice. I wouldn't spend crazy money on that table though, you might be better off spending that money getting a 5 series or 7 Series Music Hall second hand and putting the cartridge you have on it. My 5.1 sounded better with a $50 AT95e on it than the 2.2 with the mp500 on it.