Depends on a couple of things. No issue between the speakers if several feet behind (4 feet or more) behind the speakers and low to the floor. My gear is is only two feet off the floor and a therefore a non-issue.
Now, if your gear is on the same plane as your speakers and stand/gear 3-6 feet high, your sound will suffer.
Now, if your gear is on the same plane as your speakers and stand/gear 3-6 feet high, your sound will suffer.