Question?
The orginal post states 2x4 stick construction.
The floor joists (garage rafters) are 2x4's as well? Not 2x6's?
If the floor joists really are 2x4's they are then most likely on 18 or 24 inch centers.
If so... splurge and hire a structural engineer (or competent "truly" professional carpenter) to come in and assess the situation.
Is the center ridge in the garage still straight?
If the previous owners totally ignored sound construction practices in their effort to save some $$$ in this DIY room there might be bigger issues than what you know.
The orginal post states 2x4 stick construction.
The floor joists (garage rafters) are 2x4's as well? Not 2x6's?
If the floor joists really are 2x4's they are then most likely on 18 or 24 inch centers.
If so... splurge and hire a structural engineer (or competent "truly" professional carpenter) to come in and assess the situation.
Is the center ridge in the garage still straight?
If the previous owners totally ignored sound construction practices in their effort to save some $$$ in this DIY room there might be bigger issues than what you know.

