Bypassing ’lytics in power supplies is definitely a notable improvement- second only to using large film or motor-run caps (in my opinion). In speakers, I find it a mixed bag, but have had "decent" results in bypassing a large series midrange band-pass capacitor in the high pass of the midrange circuit. In most cases those don’t get much bigger than 20-40 uf for the most part, so just replacing them using a mid to high-quality film can still be budget-friendly (and more practical). Large films do take up lots of space for sure. In fact in some of the smaller monitors I’ve built, I’ve even re-calculated the net internal enclosure volume to counter the volume displacement of the large cans!