Why not cryo AFTER break in of product?

I would think that due to the fact that cryo treatment changes the structure of the metal conductor at the molecular level, that you would have to break the cable in all over again. Why would you want to have to break the cable in twice?

If you are writing about cables, just moving the cables around, bending them, unbending them.. messes up the 'break-in'. Ditto after a cable is cryo'ed. The more you bend/twist it, the the more "un-cryo'ed" it's going to be.
And has anyone had experience with a cryo'ed cable, that was so rebent, retwisted and replaced after the cryo, it totally lost all the benefits of the cryo?
Ditto single crystal copper cables, the more they get bent, twisted, replaced and recoiled again.. the more broken up the crystaline structure will be. (One reason to be careful about used cables of this type!)

Rcrerar are implying that break-in does not effect the molecular level of the conductor?