Actually, I am like Sounds_real also on this.
I do not sweat changes that make small differences.
I have found some "tweaks" can make a big difference though, often similar in magnitude to a change from one good source or amp to another.
I don't know if I'd say I've ever heard a tweak make as much difference as can be had by changing speakers though.
Tweaks also have smaller downsides when they don't work out for the better than the other bigger changes.
I do not sweat changes that make small differences.
I have found some "tweaks" can make a big difference though, often similar in magnitude to a change from one good source or amp to another.
I don't know if I'd say I've ever heard a tweak make as much difference as can be had by changing speakers though.
Tweaks also have smaller downsides when they don't work out for the better than the other bigger changes.

