Geoff--I asked the question of anyone who may be aware--of course, if inherent directionality was noted in other applications, it might support the directionality camp. Their research and usage could have some transferable context.
If not, I would think that the absence of it in other applications where stakes are infinitely higher and arguably more sensitive than our measly listening devices would support the non-directionality camp.
Then, of course, perhaps one could argue that it's apples to oranges and that there is something inherently electrically different and unique about audio from everything else. Couldn't definitively argue against that. I have a difficult time believing "we" are that unique, though.
I didn't take Almarg's response as anything other than experiential and anecdotal, which he qualified, FWIW. You may know him well enough to read between lines. I dunno.
Anyway, I have not been able to detect any difference from flipping cables around, but I, of course, have stone ears, crappy gear, and am too dumb to even understand how MQA is supposed to work. And I use comparatively inexpensive (so, probably crappy) cables--mostly stranded copper speaker, rca, and xlr. A couple of rcas with a touch of silver. Silver plated solid copper for digital, because I got a deal on them. Might directionality only apply to premium cabling?